The Men's Health Investigation Network

What is Testosterone Gel?

Low testosterone in men caused by various conditions is most often treated with testosterone gel (t gel). This prescription medication is a type of hormone replacement therapy and works by increasing testosterone in the body to a normal level.

Testosterone Gel Side Effects:

  • Acne
  • Enlarged prostate
  • Headache
  • Gynecomastia
  • Heart problems
  • Fluid retention
  • Harm to close contacts

Other Testosterone Gel Considerations:

History has shown that hormone replacement therapy with t gel can be dangerous. That fact became evident for females in 2002 when a landmark study shook up the conventional wisdom about the benefits of estrogen replacement therapy for menopause, the period when women stop producing eggs and estrogen. The federal study showed that women taking hormone pills were more likely to suffer heart attacks, breast cancer and strokes. Doctors now generally recommend hormones only to relieve severe menopause symptoms.

In addition, testosterone gel can cause shrinkage of the testicles and infertility:

“A man’s body (actually certain key parts of his brain) constantly monitors the level of testosterone in his blood. When levels fall, the brain sends signals to the testicles to boost production, and when levels rise, the brain tells the testicles to shut down. Adding extra testosterone, in other words, tricks the brain and causes it to send signals that not only shut down testosterone production, but sperm production as well. The result are smaller, softer testicles, and infertility.”


When faced with low testosterone, one should consider all of the treatment options options, including safe, natural testosterone supplements.

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